Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905906 | 1.00 | LMNA (0.32) | LMNADGAT1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL6906012 | 0.80 | P4HB (0.40) | LMNADGAT1ALDH1A1 | |
| SCHEMBL6906011 | 0.80 | P4HB (0.40) | LMNADGAT1ALDH1A1 | |
| SCHEMBL6904875 | 0.77 | HSP90AA1 (0.36) | LMNADGAT1KDM4EALDH1A1HSP90AA1 | |
| SCHEMBL6905827 | 0.72 | GAA (0.41) | DGAT1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3939670 | 0.70 | TBXAS1 (0.34) | DGAT1 | |
| SCHEMBL3070906 | 0.70 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL5879334 | 0.69 | MAPT (0.40) | LMNADGAT1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL1767760 | 0.69 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL16203617 | 0.68 | ACHE (0.35) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110764-A1 | Inhibitors of prenyl-protein transferase | STUMP CRAIG A (US) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110764-A1 | Inhibitors of prenyl-protein transferase | FNTA, KRAS, PTAR1 | LMNA 3435/4885DGAT1 334/4885KDM4E 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.