SCHEMBL6905649

SCHEMBL6905649

O=[PH](OC(c1ccccc1)(c1ccccc1)c1ccccc1)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.40
MAPK1 P28482 1/20 0.37
KCNN4 O15554 4/20 0.36
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
PTPN1 P18031 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
CES1 P23141 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
MAPT P10636 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8825906 0.88 CYP19A1 (0.40) KIF11TSHRCYP1A2KMT2AMEN1
SCHEMBL8825816 0.84 KIF11 (0.45) KIF11KMT2ACES1CA1CA2
SCHEMBL6905650 0.81 KCNN4 (0.38) KIF11MAPK1KCNN4TSHRALDH1A1
SCHEMBL3887648 0.78 MAPK1 (0.46) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL3178208 0.76 GABRP (0.30)
SCHEMBL11850439 0.76 KCNN4 (0.38) MAPK1KCNN4TSHRALDH1A1CYP1A2
SCHEMBL20815738 0.76 ALDH1A1 (0.44) KIF11MAPK1KCNN4TSHRALDH1A1
SCHEMBL11020718 0.73 TSHR (0.36) KIF11MAPK1KCNN4TSHRALDH1A1
SCHEMBL8825910 0.72 CYP19A1 (0.38) KIF11MAPK1TSHRCYP1A2KMT2A
SCHEMBL3250919 0.70 KIF11 (0.44) KIF11MAPK1KCNN4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019018655-A1 SYNTHESIS OF BIOCOMPATIBLE TRITYL RADICALS FOR APPLICATIONS AS HYPERPOLARIZATION AGENTS WEST VIRGINIA UNIVERSITY (US) 2019-01-24 WO disclosed
US-20040044168-A1 Phosphorus- and nitrogen-containing resin hardener and a flame retarding resin composition containing said hardener CHANG CHUN PLASTICS CO., LTD. (TW) 2004-03-04 US disclosed
US-6617028-B1 Oxaphosphophenanthranene-substituted melamines or diaminotriazines; epoxy resins CHANG CHUN PLASTICS CO., LTD. (TW) 2003-09-09 US disclosed
US-5786401-A CONCURRENT BLOWING, MOLDING OF POLYURETHANE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-07-28 US disclosed
US-5741825-A CLOSED CELL FOAM FOR HEAT RESISTANCE FORMED BY BLOWING WITH IODOFLUOROHYDROCARBONS AND HYDROGEN CONTAINING FLUOROMORPHOLINE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-04-21 US disclosed
EP-0700953-A2 Thermal insulating foamed material and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-03-13 EP disclosed