Pyridine

Pyridine

SCHEMBL6905947

C[Si](C)(C)n1ccnc1.c1ccncc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
NAPRT Q6XQN6 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
QPCT Q16769 2/20 0.37
QPCTL Q9NXS2 2/20 0.37
NFKB1 P19838 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP3A4 P08684 3/20 0.34
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
CYP19A1 P11511 2/20 0.31
CYP2A6 P11509 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
TBXAS1 P24557 1/20 0.31
CYP4Z1 Q86W10 1/20 0.31
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217284 0.88
Bromide SCHEMBL28508208 0.85 NFKB1 (0.43) QPCTQPCTLNFKB1HSD17B10CYP3A4
Pyridine SCHEMBL28304645 0.78 TSHR (0.47) TSHRNAPRTTDP1
1-Methylimidazole SCHEMBL29178524 0.77 NFKB1 (0.68) QPCTQPCTLNFKB1HSD17B10TBXAS1
SCHEMBL10503985 0.72 NFKB1 (0.46) QPCTQPCTLNFKB1HSD17B10CYP3A4
1-Methylimidazole SCHEMBL11368070 0.71 QPCT (0.75) TSHRNAPRTTDP1QPCTQPCTL
1-Methylimidazole SCHEMBL4991962 0.71 QPCT (0.75) TSHRNAPRTTDP1QPCTQPCTL
1-Methylimidazole SCHEMBL28150706 0.70 QPCT (0.71) TSHRNAPRTTDP1QPCTQPCTL
1-Methylimidazole SCHEMBL3328112 0.70 QPCT (0.71) TSHRNAPRTTDP1QPCTQPCTL
Pyridine SCHEMBL27779675 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111900477-A High-voltage lithium ion battery electrolyte film-forming additive, electrolyte and battery thereof 松山湖材料实验室 2020-11-06 CN claimed
US-12636301-B2 5′-modified carbocyclic ribonucleotide derivatives and methods of use SANEGENE BIO USA INC. (US) 2026-05-26 US disclosed
EP-4676497-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CELL DEATH INDUCING DFFA LIKE EFFECTOR B (CIDEB) Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
EP-4638742-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2025-10-29 EP disclosed
EP-4630556-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING 3 (PNPLA3) Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2025-10-15 EP disclosed
WO-2025108284-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF SODIUM VOLTAGE-GATED CHANNEL ALPHA SUBUNIT 9 (SCN9A) SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD. (CN) 2025-05-30 WO disclosed
WO-2025040097-A1 SIRNA TARGETING ANGPTL4, AND CONJUGATE AND USE THEREOF 成都先衍生物技术有限公司 2025-02-27 WO disclosed
EP-4482845-A1 5'-MODIFIED CARBOCYCLIC RIBONUCLEOTIDE DERIVATIVES AND METHODS OF USE Sanegene Bio USA Inc. (US) 2025-01-01 EP disclosed
CN-118922431-A 5' -Modified carbocyclic ribonucleotide derivatives and methods of use 美国圣因生物股份有限公司 2024-11-08 CN disclosed
WO-2024227458-A2 SIRNA TARGETING AGT GENE EXPRESSION AND CONJUGATE AND USE THEREOF 成都先衍生物技术有限公司 2024-11-07 WO disclosed
EP-3786623-A1 OPTIMIZED ANALYTE DERIVATIZATION FOR SYNERGISTIC APPLICATION WITH CRYSTAL SPONGE METHOD Merck Patent GmbH (DE) 2021-03-03 EP disclosed
CN-111900477-A High-voltage lithium ion battery electrolyte film-forming additive, electrolyte and battery thereof 松山湖材料实验室 2020-11-06 CN disclosed
US-6825173-B2 ANTIDIABETIC AGENTS; UROGENITAL DISORDERS CORNELL RESEARCH FOUNDATION, INC. 2004-11-30 US disclosed
US-20030130208-A1 Preparation of fagopyritols and uses therefor OBENDORF RALPH L (US) 2003-07-10 US disclosed
US-6492341-B1 Preparation of fagopyritols and uses therefor CORNELL RESEARCH FOUNDATION, INC. 2002-12-10 US disclosed
WO-2001089532-A1 PREPARATION OF FAGOPYRITOLS AND USES THEREFOR CORNELL RESEARCH FOUNDATION, INC. (US) 2001-11-29 WO disclosed
US-5633356-A RADIOACTIVE INTERMEDIATE METABOLITE FOR USE IN DIAGNOSTIC TESTING KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1997-05-27 US disclosed
US-5623063-A USING CARBON ISOTOPE-LABELLED GLUCOSE AS STARTING MATERIAL KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1997-04-22 US disclosed
US-5618734-A USING A LABELLED CARBON COMPOUND AS AN INTERNAL STANDARD; USEFUL IN DIAGNOSING DIABETES AND KIDNEY DISEASES KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1997-04-08 US disclosed
EP-0645625-A1 3-Deoxyglucosone derivatives and method for determining the same KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130208-A1 Preparation of fagopyritols and uses therefor FBP1, ALDOA, PFKFB1 TSHR 3460/4885NAPRT 298/4885TDP1 3851/4885
US-12636301-B2 5′-modified carbocyclic ribonucleotide derivatives and methods of use NSUN2, RNASE1, RNASEL TSHR 258/4885NAPRT 2214/4885TDP1 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.