Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899752 | 0.73 | MAPT (0.35) | METAP1 | |
| SCHEMBL25470451 | 0.69 | MAPT (0.38) | — | |
| SCHEMBL8204767 | 0.68 | BCHE (0.47) | METAP1 | |
| SCHEMBL12879668 | 0.67 | — | — | |
| SCHEMBL4900031 | 0.66 | RAB9A (0.42) | — | |
| SCHEMBL30211013 | 0.66 | RAB9A (0.42) | — | |
| Hydrochloric Acid SCHEMBL27998346 | 0.64 | — | — | |
| SCHEMBL14407364 | 0.59 | NR1H2 (0.35) | — | |
| SCHEMBL586534 | 0.59 | NR1H2 (0.50) | — | |
| Hydrochloric Acid SCHEMBL7945374 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693156-B1 | SIMPLY AND EFFICIENTLY SYNTHESIZED MATERIALS WITH VARIED SUBSTITUTION FOR TAILORED POLYMER PROPERTIES | BASELL POLYOLEFINE GMBH (DE) | 2004-02-17 | — | — | US | disclosed |