Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304795 | 0.89 | CLPP (0.43) | ALDH1A1KDM4EAKR1B1CLPP | |
| SCHEMBL6907587 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAACHESLC6A5 | |
| SCHEMBL2301158 | 0.85 | CLPP (0.45) | ALDH1A1KDM4EACHECYP1A2CYP2C9 | |
| SCHEMBL2345722 | 0.85 | DRD2 (0.47) | ALDH1A1KDM4EHDAC1HDAC6ACHE | |
| SCHEMBL6908503 | 0.85 | ACHE (0.48) | ALDH1A1KDM4EAKR1B1ACHESLC6A5 | |
| SCHEMBL2351132 | 0.80 | DRD4 (0.43) | ALDH1A1KDM4EHDAC1HDAC6SLC6A5 | |
| SCHEMBL2301297 | 0.76 | ACHE (0.54) | ALDH1A1KDM4EAKR1B1ACHESLC6A5 | |
| SCHEMBL2302234 | 0.76 | AKR1C3 (0.43) | ALDH1A1KDM4ECLPPMEN1KMT2A | |
| SCHEMBL6908510 | 0.75 | ACHE (0.46) | AKR1B1ACHESLC6A5CLPPMEN1 | |
| SCHEMBL2304453 | 0.75 | DRD4 (0.44) | ALDH1A1KDM4EACHECLPPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101804-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |