Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6909737 | 0.85 | BCHE (0.36) | HTR6BCHEACHECNR1 | |
| Hydrochloric Acid SCHEMBL6907085 | 0.79 | BCHE (0.37) | HTR6BCHEACHECNR1 | |
| Hydrochloric Acid SCHEMBL5599308 | 0.73 | ACHE (0.42) | HTR6BCHEACHECNR1 | |
| Hydrochloric Acid SCHEMBL30568155 | 0.73 | ACHE (0.42) | HTR6BCHEACHECNR1 | |
| Hydrochloric Acid SCHEMBL3678035 | 0.71 | ACHE (0.40) | HTR6BCHEACHECNR1 | |
| SCHEMBL6908254 | 0.70 | HTR6 (0.35) | HTR6BCHEACHEPTGS2CNR1 | |
| Hydrochloric Acid SCHEMBL27499718 | 0.70 | ACHE (0.39) | HTR6BCHEACHECNR1 | |
| Hydrochloric Acid SCHEMBL6909984 | 0.68 | PTGS2 (0.35) | PTGS2CES2CES1 | |
| SCHEMBL9959356 | 0.68 | PTPN1 (0.43) | HTR6BCHEACHECNR1 | |
| SCHEMBL8158527 | 0.67 | ACHE (0.39) | HTR6BCHEACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |