SCHEMBL6908663

SCHEMBL6908663

CC(N)C(=O)C(CS(=O)(=O)O)NC(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.52
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
CTSS P25774 3/20 0.49
CTSL P07711 2/20 0.49
CTSB P07858 2/20 0.49
CA5A P35218 1/20 0.48
ATM Q13315 1/20 0.48
CA1 P00915 3/20 0.48
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
MMP13 P45452 3/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6912269 0.99 CTSK (0.51) CTSKALDH1A1ALOX15CTSSCTSL
SCHEMBL26459466 0.85 ALDH1A1 (0.57) CTSKALDH1A1ALOX15CTSSCTSL
SCHEMBL31047722 0.85 KYNU (0.59) CTSKALDH1A1ALOX15CTSSCTSL
SCHEMBL22783671 0.84 PPARA (0.53) CTSKCTSSCTSLCTSBCA1
SCHEMBL6051919 0.83 CTSK (0.49) CTSKALDH1A1ALOX15CTSSCTSL
SCHEMBL6912965 0.82 CTSK (0.48) CTSKALDH1A1ALOX15CTSSCTSL
Phosphonic Acid SCHEMBL7620939 0.81 ALDH1A1 (0.62) CTSKALDH1A1ALOX15CTSSCTSL
Phosphoric Acid SCHEMBL7625630 0.81 CTSK (0.52) CTSKALDH1A1ALOX15CTSSCTSL
Alanine SCHEMBL28766518 0.80 CTSK (0.56) CTSKALDH1A1ALOX15CTSSCTSL
SCHEMBL6140023 0.77 ATM (0.61) CTSKCTSSCTSLCTSBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6762174-B1 BETA-ALETHINE WITH MELPHALAN OR CYCLOPHOSPHAMIDE; PREVENTS CLINICAL APPEARANCE OF A NEOPLASTIC OR PRE-NEOPLASTIC CONDITION; IMMUNOMODULATION; ENHANCING CELL GROWTH, VITALITY, DIFFERENTIATION; ANTISENESCENCE DOVETAIL TECHNOLOGIES, INC. 2004-07-13 US disclosed
US-6498150-B2 USEFUL IN ENHANCING VACCINATION, INCREASING SYNTHESIS AND FUNCTION OF BLOOD CELL COMPONENTS, AND ENHANCING ANTITUMOR EFFECTS DOVETAIL TECHNOLOGIES, INC. 2002-12-24 US disclosed
US-6451853-B1 Small molecules that elicit a polarized Th1 response and for modulation of cellular immunity DOVETAIL TECHNOLOGIES, INC 2002-09-17 US disclosed
US-20020035118-A1 LOW MOLECULAR WEIGHT CELL, BONE MARROW AND IMMUNE STIMULANTS DOVETAIL TECHNOLOGIES INC. 2002-03-21 US disclosed
US-6007819-A Methods of inducing immunity using low molecular weight immune stimulants DOVETAIL TECHNOLOGIES, INC. (US) 1999-12-28 US disclosed
WO-1999042099-A1 LOW MOLECULAR WEIGHT COMPOUNDS ADMINISTERED TOGETHER WITH ANTI-CANCER AGENTS TO TREAT CANCER AND PHARMACEUTICAL COMPOSITIONS THEREOF DOVETAIL TECHNOLOGIES INC. (US) 1999-08-26 WO disclosed
WO-1997014306-A1 LOW MOLECULAR WEIGHT CELL, BONE MARROW AND IMMUNE STIMULANTS DOVETAIL TECHNOLOGIES, INC. (US) 1997-04-24 WO disclosed
US-4218404-A HYPOGLYCEMIC AGENTS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1980-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035118-A1 LOW MOLECULAR WEIGHT CELL, BONE MARROW AND IMMUNE STIMULANTS ACP1, CD14, HPGDS CTSK 1049/4885ALDH1A1 4086/4885ALOX15 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.