Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949111 | 0.99 | HTT (0.35) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6910553 | 0.80 | APAF1 (0.33) | HTTALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6904356 | 0.79 | MAPT (0.35) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6911052 | 0.78 | BCHE (0.37) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6909565 | 0.74 | CACNA1G (0.37) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6903006 | 0.66 | APAF1 (0.36) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6908963 | 0.63 | HTT (0.36) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| Lithium SCHEMBL7949113 | 0.62 | HTT (0.35) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL7949108 | 0.62 | HTT (0.35) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL3273386 | 0.58 | IDO1 (0.54) | HTTALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |