Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | APAF1 | O14727 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910553 | 0.99 | APAF1 (0.33) | MAPTAPAF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6903006 | 0.85 | APAF1 (0.36) | MAPTAPAF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6911052 | 0.82 | BCHE (0.37) | MAPTAPAF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6908964 | 0.79 | HTT (0.36) | MAPTAPAF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7949111 | 0.78 | HTT (0.35) | MAPTAPAF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6908346 | 0.74 | ALDH1A1 (0.31) | ALDH1A1NPSR1 | |
| SCHEMBL7510367 | 0.73 | GPR3 (0.36) | LMNAPOLBMEN1KMT2A | |
| SCHEMBL6909662 | 0.73 | GPR3 (0.31) | — | |
| SCHEMBL6907620 | 0.72 | TSHR (0.35) | MAPTAPAF1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL540904 | 0.72 | GPR3 (0.35) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |