Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918202 | 0.77 | OPRM1 (0.38) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL6904187 | 0.76 | PTGS2 (0.40) | PTGS2KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL6904263 | 0.74 | PTGS2 (0.44) | PTGS2KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL6912699 | 0.74 | LMNA (0.43) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL6917367 | 0.72 | CYP3A4 (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL6900835 | 0.72 | HSD17B10 (0.40) | PTGS2KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL6905862 | 0.72 | TDP1 (0.44) | PTGS2KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL9397846 | 0.72 | PTGS2 (0.48) | PTGS2KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL22308521 | 0.71 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL20164280 | 0.71 | TSPO (0.44) | PTGS2KDM4EHSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |