SCHEMBL6909425

SCHEMBL6909425

Fc1ccc(F)c(-c2cc(C(F)(F)F)n[nH]2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC8 Q09428 1/20 0.36
KCNJ11 Q14654 1/20 0.36
IDO1 P14902 1/20 0.36
TRPA1 O75762 3/20 0.35
NPC1 O15118 4/20 0.35
MAPT P10636 4/20 0.35
ALOX15 P16050 4/20 0.35
MEN1 O00255 3/20 0.35
RAB9A P51151 3/20 0.35
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MAPK1 P28482 2/20 0.35
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALOX12 P18054 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911265 0.87 ABCC8 (0.45) ABCC8KCNJ11TRPA1NPC1MAPT
SCHEMBL13024369 0.81 SMN1; SMN2 (0.47) IDO1TRPA1NPC1MAPTALOX15
SCHEMBL19879314 0.81 ABCC8 (0.35) ABCC8KCNJ11IDO1TRPA1NPC1
SCHEMBL6331111 0.77 AXL (0.54) NPC1MAPTMEN1RAB9AKMT2A
SCHEMBL15375205 0.75 CA2 (0.33) IDO1
SCHEMBL867635 0.74 ABCC8 (0.38) ABCC8KCNJ11NPC1MAPTALOX15
SCHEMBL2870717 0.73 IDO1 (0.46) IDO1NPC1MAPTALOX15MEN1
SCHEMBL16404995 0.72 ALPL (0.38) ABCC8KCNJ11NPC1MAPTALOX15
SCHEMBL16405017 0.72 ABCC8 (0.37) ABCC8KCNJ11TRPA1MAPTMEN1
SCHEMBL20414938 0.70 ABCC8 (0.38) ABCC8KCNJ11TRPA1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0791571-B1 Benzoyl derivatives BAYER CROPSCIENCE AG (DE) 2004-06-16 EP disclosed
EP-0553307-B1 HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES MONSANTO CO (US) 1998-12-09 EP disclosed
EP-0791571-A1 Benzoyl derivatives MONSANTO COMPANY (US) 1997-08-27 EP disclosed
US-5536700-A Herbicidal compositions comprising aryl-5-haloalkylpyrazoles and glyphosate, it's salts, diquat or paraquat MONSANTO COMPANY (US) 1996-07-16 US disclosed
US-5530126-A ALKYLATION IN INERT SOLVENT MONSANTO COMPANY (US) 1996-06-25 US disclosed
US-5496956-A BY ESTERIFICATION OF CARBOXY SUBSTITUTION WITH ALCOHOLS IN THE PRESENCE OF MINERAL ACID MONSANTO COMPANY (US) 1996-03-05 US disclosed
US-5489571-A CROP-SAFE COMPOUNDS EFFECTIVE AT LOW CONCENTRATIONS MONSANTO COMPANY (US) 1996-02-06 US disclosed
US-5281571-A Herbicidal benzoxazinone- and benzothiazinone-substituted pyrazoles MONSANTO COMPANY (US) 1994-01-25 US disclosed
EP-0553307-A1 HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES MONSANTO COMPANY (US) 1993-08-04 EP disclosed
WO-1992006962-A1 HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES MONSANTO COMPANY (US) 1992-04-30 WO disclosed