SCHEMBL867635

SCHEMBL867635

Fc1ccc(-c2cccc(-c3cc(C(F)(F)F)n[nH]3)n2)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38
ALPL P05186 3/20 0.38
KMO O15229 1/20 0.36
SCN9A Q15858 2/20 0.34
AGER Q15109 2/20 0.34
MAPT P10636 2/20 0.33
ALOX15 P16050 2/20 0.33
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33
RELA Q04206 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
CASP1 P29466 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SENP8 Q96LD8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12322371 0.91 ALPL (0.36) ABCC8KCNJ11ALPLKMOSCN9A
SCHEMBL16405017 0.85 ABCC8 (0.37) ABCC8KCNJ11ALPLKMOMAPT
SCHEMBL16404995 0.85 ALPL (0.38) ABCC8KCNJ11ALPLKMOMAPT
SCHEMBL863740 0.84 NOTUM (0.36) ALOX15SMN1; SMN2MEN1RAB9AKMT2A
SCHEMBL17429377 0.83 LMNA (0.39) MAPTALOX15NFKB1NFKB2RELA
SCHEMBL6911265 0.83 ABCC8 (0.45) ABCC8KCNJ11ALPLMAPTALOX15
SCHEMBL18287243 0.82 KDM4E (0.46) MAPTSMN1; SMN2MEN1NPC1RAB9A
SCHEMBL863315 0.81 ALPL (0.41) ALPLKMOSCN9AAGERMAPT
SCHEMBL19072687 0.80 KMO (0.43) KMOSCN9AAGERTGFBR1ALOX5AP
SCHEMBL18290495 0.78 ALPL (0.34) ABCC8KCNJ11ALPLMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9553277-B2 Iridium complexes and organic light-emitting diodes using the same NATIONAL TSING HUA UNIVERSITY (TW) 2017-01-24 US disclosed
US-9553277-B2 Iridium complexes and organic light-emitting diodes using the same NATIONAL TSING HUA UNIVERSITY (TW) 2017-01-24 US disclosed
US-20160359129-A1 IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DIODES USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2016-12-08 US disclosed
US-20160359129-A1 IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DIODES USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2016-12-08 US disclosed
US-20160355534-A1 IRIDIUM (III) BASED PHOSPHORS BEARING PINCER CARBENE AND PYRAZOLYL CHELATES NATIONAL TSING HUA UNIVERSITY (TAIWAN) (TW) 2016-12-08 US disclosed
US-20160355534-A1 IRIDIUM (III) BASED PHOSPHORS BEARING PINCER CARBENE AND PYRAZOLYL CHELATES NATIONAL TSING HUA UNIVERSITY (TAIWAN) (TW) 2016-12-08 US disclosed
EP-2826821-A1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE ADSORPTION LIQUID COMPOSITION FOR DYE-SENSITIZED SOLAR CELL, SEMICONDUCTOR ELECTRODE FOR DYE-SENSITIZED SOLAR CELL, AND METHOD FOR PRODUCING DYE-SENSITIZED SOLAR CELL Fujifilm Corporation (JP) 2015-01-21 EP disclosed
CN-102485731-B Hybrid, double tridentate ruthenium complex and preparation of sensitized dye solar cell JI YUN 2014-12-24 CN disclosed
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
CN-102485731-A Hybrid, double tridentate ruthenium complex and preparation of sensitized dye solar cell YUN JI 2012-06-06 CN disclosed
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS NATIONAL TSING HUA UNIVERSITY (TW) 2012-03-29 US disclosed
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS NATIONAL TSING HUA UNIVERSITY (TW) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS RUVBL2, RUVBL1, CCNL2 ABCC8 3744/4885KCNJ11 2731/4885ALPL 2005/4885
US-20160359129-A1 IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DIODES USING THE SAME APOL1, SNRPD1, OCIAD1 ABCC8 4211/4885KCNJ11 3129/4885ALPL 806/4885
US-20160355534-A1 IRIDIUM (III) BASED PHOSPHORS BEARING PINCER CARBENE AND PYRAZOLYL CHELATES PIN4, ORC3, OSBPL3 ABCC8 2675/4885KCNJ11 1231/4885ALPL 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.