Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910975 | 0.81 | CA2 (0.60) | KMT2AFLT1FLT4KDRMEN1 | |
| SCHEMBL2098741 | 0.78 | FABP4 (0.51) | FLT1FLT4KDRMMP8MMP14 | |
| SCHEMBL9811918 | 0.77 | CA12 (0.69) | FLT1FLT4KDRRAB9AMMP8 | |
| SCHEMBL5320613 | 0.77 | KMT2A (0.51) | KMT2AFLT1FLT4KDRLMNA | |
| SCHEMBL4423289 | 0.76 | CA2 (0.47) | KMT2AFLT1FLT4KDRMEN1 | |
| SCHEMBL15787094 | 0.75 | APEX1 (0.62) | KMT2AALDH1A1RAB9AMEP1B | |
| SCHEMBL4423288 | 0.75 | CA2 (0.46) | KMT2AFLT1FLT4KDRMEN1 | |
| SCHEMBL6904614 | 0.75 | ALDH1A1 (0.56) | KMT2ALMNAMEN1ALDH1A1MMP8 | |
| SCHEMBL11764883 | 0.75 | MMP2 (0.60) | KMT2ALMNAMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13485852 | 0.73 | CA1 (0.64) | FLT1FLT4KDRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048393-A2 | NOVEL INHIBITORS OF β-LACTAMASE | METHYLGENE, INC. (CA) | 2004-06-10 | — | — | WO | disclosed |