Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909785 | 0.93 | BRS3 (0.44) | BRS3ALDH1A1KDM4EGAAHTR1A | |
| SCHEMBL6911739 | 0.90 | SLC6A5 (0.42) | GAAHTR1AADORA1DRD2SLC6A5 | |
| SCHEMBL2356534 | 0.86 | TACR1 (0.46) | BRS3ALDH1A1KDM4EGAALMNA | |
| SCHEMBL6911686 | 0.85 | MEN1 (0.51) | GAATRPV1MAPTDRD2DRD3 | |
| SCHEMBL2343382 | 0.84 | UBE2M (0.41) | BRS3ALDH1A1KDM4EGAALMNA | |
| SCHEMBL6910467 | 0.82 | COMT (0.42) | KDM4EDRD2KCNH2CYP3A4POLB | |
| SCHEMBL6911338 | 0.81 | MEN1 (0.44) | ALDH1A1KDM4EGAATRPV1MAPT | |
| SCHEMBL2355502 | 0.80 | CLPP (0.52) | GAADRD2DRD3SLC6A5CYP3A4 | |
| SCHEMBL6910908 | 0.80 | KDM4E (0.46) | BRS3ALDH1A1KDM4EGAALMNA | |
| SCHEMBL2342836 | 0.80 | KCNN4 (0.41) | BRS3ALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101805-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |