Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8591755 | 1.00 | DRD2 (0.38) | DRD2HTR1ACES1HTR2ARET | |
| Hydrochloric Acid SCHEMBL6358953 | 0.79 | CES1 (0.35) | DRD2HTR1ACES1HTR2ARET | |
| Hydrochloric Acid SCHEMBL5616477 | 0.75 | HTR1A (0.38) | DRD2HTR1ACES1HTR2ARET | |
| Hydrochloric Acid SCHEMBL6904510 | 0.75 | CES1 (0.39) | DRD2HTR1ACES1HTR2ARET | |
| Hydrochloric Acid SCHEMBL2749840 | 0.72 | GPR3 (0.32) | — | |
| SCHEMBL3112713 | 0.70 | HTR1A (0.41) | DRD2HTR1ACES1HTR2ARET | |
| SCHEMBL9217926 | 0.68 | CES1 (0.36) | DRD2HTR1ACES1HTR2ARET | |
| SCHEMBL1087686 | 0.68 | GID4 (0.43) | DRD2HTR1A | |
| SCHEMBL1304934 | 0.67 | HTR2A (0.48) | HTR1AHTR2A | |
| SCHEMBL29490167 | 0.67 | HTR2A (0.48) | HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832753-B1 | MULTIMODAL POLYOLEFIN RESIN AND MOLDED PRODUCT PREPARED THEREFROM | DAELIM IND CO LTD (KR) | 2018-04-11 | — | — | EP | disclosed |
| EP-2832753-A1 | MULTIMODAL POLYOLEFIN RESIN AND MOLDED PRODUCT PREPARED THEREFROM | Daelim Industrial Co., Ltd. (KR) | 2015-02-04 | — | — | EP | disclosed |
| EP-0996647-B1 | PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION | BOREALIS TECH OY (FI) | 2004-09-08 | — | — | EP | disclosed |
| EP-0996647-A1 | PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION | BOREALIS A/S (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999003897-A1 | PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION | BOREALIS A/S (DK) | 1999-01-28 | — | — | WO | disclosed |