SCHEMBL6911832

SCHEMBL6911832

CCc1ccc2c(c1)CC(C)(c1cc(CC)c(O)c(CC)c1)C(C)(C)O2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.34
RAB9A P51151 2/20 0.33
MAPK1 P28482 1/20 0.33
CTSB P07858 1/20 0.33
HIF1A Q16665 3/20 0.32
EPAS1 Q99814 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TRPA1 O75762 1/20 0.31
SLC5A1 P13866 2/20 0.30
SLC5A2 P31639 2/20 0.30
MGAM O43451 2/20 0.30
GAA P10253 2/20 0.30
SI P14410 2/20 0.30
MGAM2 Q2M2H8 2/20 0.30
EDNRA P25101 1/20 0.30
HCAR3 P49019 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27347883 0.77 RAB9A (0.34) PARP1RAB9AMAPK1CTSBMEN1
SCHEMBL8225530 0.72 HIF1A (0.44) PARP1CTSBHIF1AEPAS1MEN1
SCHEMBL4631381 0.71 ACHE (0.34) MEN1KMT2AATML3MBTL1GAA
SCHEMBL6909858 0.70 AKR1C1 (0.35) RAB9AGAAMAPT
SCHEMBL6836965 0.70 FTO (0.38) PARP1RAB9AMEN1KMT2ATRPA1
SCHEMBL6910911 0.70 AKR1B1 (0.37) PARP1RAB9ACTSBMEN1KMT2A
SCHEMBL27447416 0.64 MEN1 (0.32) PARP1RAB9AMEN1KMT2AEDNRA
SCHEMBL27457712 0.64 MEN1 (0.32) PARP1RAB9AMEN1KMT2AEDNRA
SCHEMBL27350972 0.64 MEN1 (0.32) PARP1RAB9AMEN1KMT2AEDNRA
SCHEMBL27458584 0.64 MEN1 (0.32) PARP1RAB9AMEN1KMT2AEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756432-B2 POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-29 US disclosed
EP-0736574-B1 Thermoplastic resin composition comprising carbonate and acrylic resin GEN ELECTRIC (US) 2004-06-02 EP disclosed
US-20030153655-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 US disclosed
EP-0685526-B1 Fire-resistant polycarbonate resin composition GEN ELECTRIC (US) 2001-08-29 EP disclosed
US-6197917-B1 Method for manufacturing polycarbonate for optical use GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
EP-1070743-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 2001-01-24 EP disclosed
US-6103827-A A TRANSPARENT THERMOPLASTIC RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-08-15 US disclosed
US-6043310-A FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. GENERAL ELECTRIC COMPANY (US) 2000-03-28 US disclosed
EP-0561630-B1 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LTD (JP) 1999-12-29 EP disclosed
US-5883194-A RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS GENERAL ELECTRIC COMPANY (US) 1999-03-16 US disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed