SCHEMBL4631381

SCHEMBL4631381

Cc1ccc2c(c1)CC(C)(c1cc(C)c(O)c(C)c1)C(C)(C)O2

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.34
KDM4E B2RXH2 5/20 0.32
ATM Q13315 2/20 0.32
RAD52 P43351 1/20 0.32
ALOX5 P09917 2/20 0.31
PTGS1 P23219 2/20 0.31
PTGS2 P35354 2/20 0.31
GAA P10253 2/20 0.31
MEN1 O00255 1/20 0.31
G6PD P11413 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PTPN1 P18031 1/20 0.31
HTT P42858 2/20 0.30
ALDH1A1 P00352 1/20 0.30
F2 P00734 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835938 0.79 ACHE (0.35) ACHEKDM4EGAAALDH1A1
SCHEMBL6909858 0.74 AKR1C1 (0.35) KDM4EGAAPTPN1HTTALDH1A1
SCHEMBL6911832 0.71 PARP1 (0.34) ATMGAAMEN1KMT2AL3MBTL1
SCHEMBL12856785 0.71 KDM4E (0.44) KDM4EATMRAD52GAAPTPN1
SCHEMBL12035985 0.70 MAPT (0.41) KDM4EATMRAD52GAAMEN1
SCHEMBL25513578 0.70 IRAK4 (0.36) KDM4EATMRAD52PTGS1PTGS2
SCHEMBL27454580 0.70 ALOX5 (0.34) ACHEKDM4EALOX5PTGS1PTGS2
SCHEMBL25513496 0.68 HTR1A (0.37) KDM4EATMRAD52GAAMEN1
SCHEMBL17193794 0.67 KDM4E (0.37) KDM4EATMRAD52GAAPTPN1
SCHEMBL6912343 0.67 ALOX15 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP claimed
EP-1472302-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2004-11-03 EP claimed
WO-2002046272-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2002-06-13 WO claimed
CN-100445316-C Recycling process for polycondensation resins GEN ELECTRIC (US) 2008-12-24 CN disclosed
EP-1156071-B2 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2008-08-06 EP disclosed
EP-1151027-B1 OPTICAL DISC COMPRISING POLYCARBONATE WITH REDUCED LEVELS OF FRIES GEN ELECTRIC (US) 2008-05-14 EP disclosed
EP-1490422-B1 RECYCLE PROCESS FOR POLYCONDENSATION RESINS GEN ELECTRIC (US) 2006-10-04 EP disclosed
US-7112645-B2 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate GENERAL ELECTRIC COMPANY (US) 2006-09-26 US disclosed
EP-1141082-B1 METHOD OF MANUFACTURING POLYCARBONATES GEN ELECTRIC (US) 2005-11-30 EP disclosed
WO-2005092951-A1 A POLYCARBONATE COMPOSITION AND METHOD OF MAKING THEREOF GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-10-06 WO disclosed
CN-1221590-C Optical polycarbonate and application thereof GEN ELECTRIC (US) 2005-10-05 CN disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed