Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498281 | 0.73 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL809567 | 0.68 | LMNA (0.39) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL777177 | 0.68 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL11013481 | 0.67 | LMNA (0.42) | LMNASMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL6915326 | 0.67 | MAOA (0.46) | ALDH1A1NPC1RAB9A | |
| SCHEMBL23964577 | 0.65 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL9550729 | 0.65 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL809548 | 0.65 | LMNA (0.37) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL776362 | 0.64 | MAOA (0.41) | LMNASMN1; SMN2MAPTHPGDMGLL | |
| SCHEMBL10936991 | 0.64 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2MAPTHPGDMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818423-B2 | LOW-MOLECULAR-WEIGHT C4-C6-KETONES DERIVATIZED WITH REMOVABLE GROUP ARE REACTED WITH CYANIDE GROUP DONOR IN PRESENCE OF HYDROXYNITRILE LYASE OR BY RACEMIC REACTION, ACIDIC HYDROLYSIS, OPTIONALLY RESOLUTION, AND CLEAVAGE OF THE GROUP | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AU) | 2004-11-16 | — | — | US | disclosed |
| US-20030092142-A1 | Process for the preparation of chiral alpha-hydroxycarboxylic acids | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2003-05-15 | — | — | US | disclosed |