Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 10/20 | 0.45 |
| ▸ | KLK7 | P49862 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558112 | 0.84 | KDM4E (0.68) | ALDH1A1KDM4EUBE2NHTR6KLK7 | |
| SCHEMBL1418894 | 0.84 | KDM4E (0.68) | ALDH1A1KDM4EUBE2NHTR6KLK7 | |
| SCHEMBL28301830 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4EUBE2NHTR6LMNA | |
| SCHEMBL2134631 | 0.81 | KDM4E (0.67) | ALDH1A1KDM4EUBE2NHTR6KLK7 | |
| SCHEMBL29111244 | 0.77 | KLK7 (0.43) | ALDH1A1KDM4EUBE2NHTR6KLK7 | |
| SCHEMBL29072201 | 0.74 | KDM4E (0.60) | ALDH1A1KDM4EUBE2NHTR6KLK7 | |
| Hydrochloric Acid SCHEMBL29047285 | 0.74 | HTR6 (0.72) | HTR6KLK7 | |
| SCHEMBL949730 | 0.72 | HTR6 (0.58) | KDM4EUBE2NHTR6KLK7 | |
| SCHEMBL28696989 | 0.72 | HTR6 (0.44) | KDM4EUBE2NHTR6KLK7FABP4 | |
| SCHEMBL3623011 | 0.72 | FABP4 (0.56) | ALDH1A1KDM4EUBE2NHTR6FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040143003-A1 | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors | MATTSON RONALD J (US) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143003-A1 | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors | HTR1A, HTR1D, TPH1 | ALDH1A1 516/4885KDM4E 3636/4885UBE2N 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.