4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL6914883

Cc1ccc(C(=O)O)cc1.[Hg]

nearest known ligand 0.94

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.94
SMN1; SMN2 Q16637 2/20 0.94
SRD5A2 P31213 3/20 0.81
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
CES2 O00748 2/20 0.62
CES1 P23141 2/20 0.62
LMNA P02545 2/20 0.62
RXRA P19793 1/20 0.58
RXRB P28702 1/20 0.58
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL11366477 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL526449 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL147465 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL15994097 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1331178 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL93638 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1150904 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL902358 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1042425 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6112949 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6830704-B2 Contains a Lewis acid metal salt and a compound having clathrating ability. TOAGOSEI CO., LTD. (JP) 2004-12-14 US disclosed
US-20030135016-A1 Contains a Lewis acid metal salt and a compound having clathrating ability. TOAGOSEI CO., LTD. 2003-07-17 US disclosed
US-6547985-B1 Adhesive mixture TOGOSEI CO., LTD. (JP) 2003-04-15 US disclosed