Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917293 | 0.76 | GAA (0.31) | LMNA | |
| SCHEMBL3281290 | 0.73 | FDPS (0.37) | LMNA | |
| SCHEMBL5665801 | 0.69 | L3MBTL1 (0.32) | LMNA | |
| SCHEMBL10942245 | 0.67 | FDPS (0.36) | — | |
| SCHEMBL3896487 | 0.67 | GRM2 (0.32) | LMNA | |
| SCHEMBL25757523 | 0.65 | TSHR (0.35) | — | |
| Phosphoric Acid SCHEMBL20817050 | 0.65 | MMP1 (0.33) | — | |
| SCHEMBL8350477 | 0.64 | MGAM (0.32) | — | |
| SCHEMBL337595 | 0.64 | MMP1 (0.34) | — | |
| SCHEMBL6910126 | 0.63 | ALDH1A1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |