Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716776 | 0.87 | PNMT (0.52) | PNMTTAAR1TSHRIDO1SMN1; SMN2 | |
| SCHEMBL29749412 | 0.80 | TSHR (0.50) | PNMTTAAR1TSHRIDO1SMN1; SMN2 | |
| SCHEMBL28326627 | 0.77 | FFAR1 (0.52) | PNMTTAAR1TSHRSMN1; SMN2PYGL | |
| SCHEMBL3393678 | 0.74 | PYGL (0.57) | PNMTTAAR1TSHRIDO1PYGL | |
| SCHEMBL7698349 | 0.74 | NPC1 (0.60) | TSHRSMN1; SMN2FFAR1 | |
| SCHEMBL27820637 | 0.73 | CYP3A4 (0.49) | PNMTTAAR1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL6078543 | 0.73 | IGF1R (0.56) | PNMTTAAR1TSHRIDO1PYGL | |
| SCHEMBL20524098 | 0.73 | IDO1 (0.58) | PNMTTAAR1TSHRIDO1SMN1; SMN2 | |
| SCHEMBL4741469 | 0.72 | FFAR1 (0.49) | PNMTTAAR1TSHRIDO1SMN1; SMN2 | |
| SCHEMBL3661748 | 0.72 | IDO1 (0.42) | PNMTTAAR1TSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |