Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922492 | 0.91 | ALDH1A1 (0.41) | MAPTLMNAPOLBNPSR1KMT2A | |
| SCHEMBL3894587 | 0.83 | PRKCA (0.36) | MAPTLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL62519 | 0.83 | LMNA (0.51) | MAPTLMNANPSR1RAB9AKMT2A | |
| SCHEMBL3390 | 0.82 | ALDH1A1 (0.55) | LMNAHPGDRAB9AKMT2AL3MBTL1 | |
| SCHEMBL4529776 | 0.82 | ALDH1A1 (0.50) | MAPTLMNAHPGDRAB9AKMT2A | |
| Benzocaine SCHEMBL7263677 | 0.79 | LMNA (0.69) | MAPTLMNANPSR1HPGDRAB9A | |
| Ether SCHEMBL13280294 | 0.78 | LMNA (0.46) | MAPTLMNARAB9AKMT2AGAA | |
| SCHEMBL775791 | 0.77 | MAPT (0.58) | MAPTLMNAPOLBNPSR1HPGD | |
| SCHEMBL6917173 | 0.76 | MAPT (0.53) | MAPTLMNAPOLBNPSR1ALDH1A1 | |
| SCHEMBL28187657 | 0.73 | MAPT (0.54) | MAPTLMNAPOLBNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720439-B1 | EFFICIENT REDUCTION OF BASE SENSITIVE CARBONYL COMPOUNDS; SEPARATING RACEMIC CARBONYL COMPOUNDS; CHIRAL CATALYSTS | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2004-04-13 | — | — | US | disclosed |