Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 10/20 | 0.48 |
| ▸ | IDO2 | Q6ZQW0 | 10/20 | 0.48 |
| ▸ | IDO1 | P14902 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412437 | 0.78 | UGT1A1 (0.65) | KMT2AMAPTNPC1RAB9AHTT | |
| Tryptanthrin SCHEMBL2426211 | 0.70 | TDO2 (1.00) | TDO2IDO2IDO1KMT2AMAPT | |
| Tryptanthrin SCHEMBL29359262 | 0.70 | TDO2 (1.00) | TDO2IDO2IDO1KMT2AMAPT | |
| SCHEMBL30537967 | 0.67 | TDO2 (0.74) | TDO2IDO2IDO1KMT2AMAPT | |
| SCHEMBL9103139 | 0.67 | TDO2 (0.74) | TDO2IDO2IDO1KMT2AMAPT | |
| SCHEMBL15951027 | 0.65 | UGT1A1 (0.46) | KMT2AMAPTNPC1RAB9AHTT | |
| SCHEMBL24513477 | 0.65 | TDO2 (0.62) | TDO2IDO2IDO1KMT2AMAPT | |
| SCHEMBL29118562 | 0.64 | FBP1 (0.65) | KMT2AMAPTLMNAALOX5HDAC6 | |
| Quercetin SCHEMBL5490220 | 0.64 | MEN1 (0.58) | KMT2AMAPTHTTLMNAALOX5 | |
| SCHEMBL24513677 | 0.63 | TDO2 (0.62) | TDO2IDO2IDO1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987027-B1 | Ethyl acetate extract from Indigo plant | HAYASHIBARA BIOCHEM LAB (JP) | 2004-08-11 | — | — | EP | claimed |