Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12408719 | 0.85 | CYP1A2 (0.47) | CYP1A2MAPTMAPK1KMT2AALOX15 | |
| SCHEMBL6225888 | 0.84 | LMNA (0.50) | MAPTHPGDNPC1 | |
| SCHEMBL17346787 | 0.83 | PADI3 (0.47) | TSHRSMN1; SMN2MEN1CYP1A2MAPT | |
| SCHEMBL6231852 | 0.82 | AOC3 (0.57) | — | |
| SCHEMBL12111459 | 0.82 | NPC1 (0.57) | TSHRSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL17549815 | 0.79 | CASP3 (0.44) | SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30069429 | 0.79 | GLS (0.55) | — | |
| SCHEMBL1165088 | 0.79 | GLS (0.55) | — | |
| SCHEMBL1903558 | 0.77 | NPSR1 (0.50) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL29675845 | 0.77 | NPSR1 (0.50) | MEN1MAPTKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021209-A1 | HISTONE DEACETYLASE INHIBITORS | PORTSMOUTH TECHNOLOGIES LLC (US) | 2011-02-24 | — | — | WO | disclosed |