Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919673 | 0.80 | KMT2A (0.41) | KMT2AALDH1A1CES2CES1L3MBTL1 | |
| SCHEMBL10755186 | 0.80 | MAPT (0.49) | KMT2AALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL6920857 | 0.77 | KDM4E (0.45) | KMT2AALDH1A1L3MBTL1LMNAKDM4E | |
| SCHEMBL10755526 | 0.77 | MAPT (0.46) | KMT2AALDH1A1L3MBTL1LMNAGLA | |
| SCHEMBL10750845 | 0.76 | ENPP3 (0.44) | KMT2AALDH1A1POLBSPR | |
| SCHEMBL13683178 | 0.75 | KMT2A (0.45) | KMT2AALDH1A1CES2CES1L3MBTL1 | |
| SCHEMBL10751104 | 0.73 | ALDH1A1 (0.40) | KMT2AALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL6921251 | 0.73 | TSHR (0.49) | KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL10752769 | 0.73 | MAPT (0.55) | KMT2AALDH1A1CES2CES1LMNA | |
| SCHEMBL10750310 | 0.73 | POLB (0.40) | KMT2AALDH1A1LMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033431-A2 | HYDROXYPYRAZOLES FOR USE AGAINST METABOLIC-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |