Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921028 | 0.84 | P2RX7 (0.38) | ALDH1A1NPC1RAB9ACES1LMNA | |
| SCHEMBL6919650 | 0.80 | KMT2A (0.46) | KMT2AALDH1A1NPC1RAB9ACES2 | |
| SCHEMBL2214214 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAL3MBTL1HTTGAA | |
| SCHEMBL6919753 | 0.76 | TDP1 (0.48) | KMT2AALDH1A1KDM4EGAAMAPT | |
| SCHEMBL6919835 | 0.71 | L3MBTL1 (0.47) | KMT2AALDH1A1NPC1RAB9ALMNA | |
| Alcohol SCHEMBL9405122 | 0.69 | KMT2A (0.62) | KMT2AALDH1A1NPC1RAB9ACES2 | |
| SCHEMBL6916937 | 0.68 | HCAR2 (0.41) | ALDH1A1NPC1RAB9ALMNAKDM4E | |
| Propylamine SCHEMBL28734534 | 0.68 | KMT2A (0.56) | KMT2AALDH1A1NPC1RAB9ACES2 | |
| SCHEMBL23399929 | 0.66 | PDE5A (0.45) | KMT2AALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL87791 | 0.66 | KMT2A (0.75) | KMT2AALDH1A1NPC1RAB9ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033431-A2 | HYDROXYPYRAZOLES FOR USE AGAINST METABOLIC-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | claimed |
| WO-2004033431-A2 | HYDROXYPYRAZOLES FOR USE AGAINST METABOLIC-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |