Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555928 | 0.84 | TSHR (0.34) | AR | |
| SCHEMBL1574267 | 0.81 | AR (0.38) | ARBCAT2BCAT1 | |
| SCHEMBL8465633 | 0.81 | AR (0.37) | ARBCAT2BCAT1 | |
| SCHEMBL8190792 | 0.79 | AR (0.39) | ARBCAT2BCAT1 | |
| SCHEMBL8464476 | 0.78 | AR (0.39) | ARBCAT2BCAT1 | |
| SCHEMBL6920290 | 0.78 | VCAM1 (0.41) | ARBCAT2BCAT1 | |
| SCHEMBL9469308 | 0.76 | POLB (0.41) | ARBCAT2BCAT1 | |
| SCHEMBL3545755 | 0.76 | MMP2 (0.36) | — | |
| SCHEMBL8936370 | 0.74 | MEN1 (0.39) | — | |
| SCHEMBL8936415 | 0.74 | GSTO1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107252-A | 1-((3-AMINOSULFONYL,4-CYANO,6-SUBSTITUTED PHENYL)-),3,4,5-SUBSTITUTED-1,2,3,6-TETRAHYDROPYRIMIDIN-2,6-DIONE COMPOUNDS; HERBICIDAL ACTIVITY AND AT THE SAME TIME COMPATIBILITY WITH CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |