Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921074 | 0.94 | TBXAS1 (0.48) | TBXAS1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL6919975 | 0.84 | F2 (0.44) | TBXAS1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL6919778 | 0.83 | ALDH1A1 (0.41) | CYP1A2CYP2A6HDAC1ALDH1A1GAA | |
| SCHEMBL6921278 | 0.83 | TSHR (0.46) | HPGDALOX15HSD17B10MAPTHTT | |
| SCHEMBL6919541 | 0.82 | HTT (0.41) | HPGDALOX15HSD17B10MAPTHTT | |
| SCHEMBL6922174 | 0.82 | MAPT (0.43) | HPGDALOX15HSD17B10MAPTHTT | |
| SCHEMBL6922335 | 0.80 | MAPT (0.41) | HPGDALOX15HSD17B10MAPTHTT | |
| SCHEMBL6919643 | 0.79 | L3MBTL1 (0.46) | TBXAS1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL6920008 | 0.78 | L3MBTL1 (0.41) | HPGDALOX15HSD17B10MAPTHTT | |
| SCHEMBL6919131 | 0.78 | ALDH1A1 (0.40) | HPGDALOX15HSD17B10MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033431-A2 | HYDROXYPYRAZOLES FOR USE AGAINST METABOLIC-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | claimed |
| WO-2004033431-A2 | HYDROXYPYRAZOLES FOR USE AGAINST METABOLIC-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |