Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 12/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921378 | 0.78 | MAPT (0.52) | MAPTL3MBTL1ALDH1A1RAB9AHPGD | |
| SCHEMBL6921135 | 0.78 | — | — | |
| SCHEMBL6918679 | 0.78 | GPR183 (0.53) | GPR183MAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL6918094 | 0.75 | RAB9A (0.56) | L3MBTL1ALDH1A1TDP1RAB9AHPGD | |
| SCHEMBL6921387 | 0.74 | L3MBTL1 (0.42) | MAPTL3MBTL1GAAALDH1A1RAB9A | |
| SCHEMBL6817246 | 0.73 | F2R (0.42) | GPR183MAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL6218242 | 0.72 | ITGAL (0.52) | MAPTL3MBTL1RAB9A | |
| SCHEMBL6921585 | 0.72 | NPC1 (0.42) | GPR183MAPTL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL6919351 | 0.71 | SMN1; SMN2 (0.53) | MAPTL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL6919430 | 0.71 | RAB9A (0.39) | MAPTL3MBTL1GAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |