Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 10/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826746 | 0.79 | CDK1 (0.44) | CDK1CDK2JAK2CDC7DBF4 | |
| SCHEMBL6917094 | 0.78 | CDK2 (0.42) | CDK1CDK2JAK2CDC7DBF4 | |
| SCHEMBL6826600 | 0.78 | CDK1 (0.53) | CDK1CDK2 | |
| SCHEMBL6824115 | 0.77 | CDK1 (0.56) | CDK1CDK2JAK2CDC7 | |
| SCHEMBL6824620 | 0.74 | CDK1 (0.49) | CDK1CDK2MAPT | |
| SCHEMBL6915719 | 0.73 | DYRK1A (0.49) | CDK1CDK2JAK2CDC7MEN1 | |
| SCHEMBL7067140 | 0.72 | CDK2 (0.46) | CDK1CDK2CDC7DBF4 | |
| SCHEMBL6823684 | 0.72 | CDK2 (0.47) | CDK1CDK2JAK2CDC7DBF4 | |
| SCHEMBL6922661 | 0.70 | CDK2 (0.51) | CDK1CDK2JAK2CDC7DBF4 | |
| SCHEMBL6920709 | 0.70 | HSP90AA1 (0.49) | CDK1CDK2JAK2CDC7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |