Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 10/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919395 | 0.91 | HTR6 (0.42) | KCNA3HTR6P2RX7 | |
| SCHEMBL6817307 | 0.82 | HTR6 (0.47) | KCNA3SCN2AHTR6 | |
| SCHEMBL6921965 | 0.76 | KCNA3 (0.47) | KCNA3SCN2ACNR1CNR2P2RX7 | |
| SCHEMBL6821065 | 0.73 | HTR6 (0.50) | HTR6 | |
| SCHEMBL6922123 | 0.71 | MAPT (0.41) | — | |
| SCHEMBL6918827 | 0.71 | HTR6 (0.44) | HTR6 | |
| SCHEMBL6820454 | 0.68 | HTR6 (0.61) | CYP1A2HTR6 | |
| SCHEMBL25322976 | 0.67 | KCNA3 (0.47) | KCNA3SCN2ACYP1A2CNR1CNR2 | |
| SCHEMBL17829679 | 0.67 | ALDH1A1 (0.57) | KCNA3CYP1A2CNR1CNR2 | |
| SCHEMBL3105145 | 0.67 | SERPINE1 (0.59) | CYP1A2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |