Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 11/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919392 | 0.90 | CHRNB2 (0.42) | KCNA3SCN2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6921968 | 0.76 | KCNA3 (0.46) | KCNA3SCN2ACNR1CNR2P2RX7 | |
| SCHEMBL6917237 | 0.76 | HTR6 (0.39) | CNR2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6817307 | 0.75 | HTR6 (0.47) | KCNA3SCN2A | |
| SCHEMBL6921379 | 0.71 | HTR6 (0.38) | — | |
| SCHEMBL6922120 | 0.70 | MAPT (0.42) | — | |
| SCHEMBL6918823 | 0.70 | AKR1C3 (0.43) | — | |
| SCHEMBL25322976 | 0.69 | KCNA3 (0.47) | KCNA3SCN2ACNR1CNR2 | |
| SCHEMBL17829679 | 0.69 | ALDH1A1 (0.57) | KCNA3CNR1CNR2 | |
| SCHEMBL3105145 | 0.69 | SERPINE1 (0.59) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |