SCHEMBL6922223

SCHEMBL6922223

C=CCSCc1ccc(O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.58
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
MIF P14174 1/20 0.45
ALOX15 P16050 5/20 0.44
IGF1R P08069 2/20 0.44
TRPA1 O75762 2/20 0.44
KDM4E B2RXH2 6/20 0.43
MAPT P10636 6/20 0.43
ALDH1A1 P00352 5/20 0.43
GAA P10253 3/20 0.43
MEN1 O00255 3/20 0.43
HPGD P15428 3/20 0.43
KMT2A Q03164 3/20 0.43
CNR1 P21554 2/20 0.43
PPARG P37231 2/20 0.43
ALDH2 P05091 1/20 0.43
GABRA1 P14867 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28996201 0.82 CA1 (0.61) XDHCA1CA2CA4CA6
SCHEMBL8539247 0.80 SMN1; SMN2 (0.50) XDHCA1CA2CA4CA6
SCHEMBL19359681 0.79 TRPA1 (0.59) XDHCA1CA2CA4CA6
SCHEMBL45130 0.79 ESR1 (0.41) XDHCA2KDM4EMAPTALDH1A1
Hydroxychavicol SCHEMBL43300 0.74 XDH (1.00) XDHCA1CA2CA4CA6
Hydroxychavicol SCHEMBL15676540 0.74 XDH (1.00) XDHCA1CA2CA4CA6
SCHEMBL9327485 0.72 ALOX5 (0.37) ALOX5CYP1A2CYP2C9
SCHEMBL6820262 0.72 TRPA1 (0.61) CA1CA2CA4CA6MIF
SCHEMBL16669214 0.71 XDH (0.64) XDHCA1CA2CA4CA6
SCHEMBL10671966 0.71 IDO1 (0.42) ALDH1A1GAAALOX5RECQLTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO claimed
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO disclosed
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO disclosed
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO disclosed