Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920592 | 0.76 | CYP3A4 (0.38) | ACHEBCHE | |
| SCHEMBL12040481 | 0.71 | ACHE (0.44) | ACHEBCHE | |
| SCHEMBL21090792 | 0.64 | CTSD (0.50) | — | |
| SCHEMBL12177192 | 0.63 | PARG (0.41) | — | |
| SCHEMBL21089924 | 0.62 | KDM4E (0.61) | — | |
| SCHEMBL12177224 | 0.58 | L3MBTL1 (0.48) | — | |
| SCHEMBL11869512 | 0.56 | ADRA1D (0.36) | — | |
| SCHEMBL8860231 | 0.54 | PARP1 (0.39) | — | |
| SCHEMBL8860237 | 0.54 | PARP1 (0.39) | — | |
| SCHEMBL24463595 | 0.53 | PDE10A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075699-A2 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | WO | disclosed |