Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | GRK1 | Q15835 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922028 | 0.85 | SLC2A1 (0.52) | RAB9ALMNASLC2A1EIF4EBP1BCL2A1 | |
| SCHEMBL12059005 | 0.77 | ICMT (0.47) | RAB9ALMNASLC2A1EIF4EBP1BCL2A1 | |
| SCHEMBL12059006 | 0.74 | RAB9A (0.54) | RAB9ALMNASLC2A1EIF4EBP1GRK2 | |
| SCHEMBL6920793 | 0.74 | ICMT (0.47) | SLC2A1EIF4EBP1GRK2GRK1ROCK2 | |
| SCHEMBL12059116 | 0.72 | ADRA1A (0.49) | RAB9ALMNASLC2A1 | |
| SCHEMBL6921556 | 0.72 | LRRK2 (0.42) | BCL2A1GRK2GRK1ALDH1A1TGFBR1 | |
| SCHEMBL6921401 | 0.69 | PRPS1 (0.49) | SLC2A1GRK2GRK1GRIN2B | |
| SCHEMBL6922249 | 0.69 | MAPT (0.46) | RAB9ALMNAEIF4EBP1GRK2GRK1 | |
| SCHEMBL6922017 | 0.69 | LMNA (0.43) | RAB9ALMNASLC2A1NPC1HPGD | |
| SCHEMBL17260401 | 0.68 | GRK2 (0.53) | RAB9ALMNASLC2A1GRK2GRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075699-A2 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | WO | disclosed |