Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | PAM | P19021 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692303 | 1.00 | CA1 (0.52) | CA1PAMMAOBIDO1HTR2A | |
| SCHEMBL4392557 | 0.77 | HTR2A (0.48) | CA1PAMMAOBIDO1HTR2A | |
| SCHEMBL9777486 | 0.75 | IDO1 (0.58) | PAMMAOBIDO1HTR2AALDH1A1 | |
| SCHEMBL4863423 | 0.75 | IDO1 (0.58) | PAMMAOBIDO1HTR2AALDH1A1 | |
| SCHEMBL526124 | 0.74 | PAM (0.54) | CA1PAMMAOBIDO1HTR2A | |
| Cinnamic Alcohol SCHEMBL4175503 | 0.73 | PAM (0.58) | CA1PAMMAOBIDO1HTR2A | |
| SCHEMBL1825137 | 0.73 | IDO1 (0.52) | PAMMAOBIDO1HTR2A | |
| Cinnamic Alcohol SCHEMBL39220 | 0.73 | PAM (0.58) | CA1PAMMAOBIDO1HTR2A | |
| Cinnamic Alcohol SCHEMBL39219 | 0.73 | PAM (0.58) | CA1PAMMAOBIDO1HTR2A | |
| Cinnamic Alcohol SCHEMBL28583889 | 0.73 | PAM (0.58) | CA1PAMMAOBIDO1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127423-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE DEUTSCHLAND (DE) | 2018-05-10 | — | — | US | disclosed |
| US-9701679-B2 | Modulators of 5-HT receptors and methods of use thereof | Abb Vie Deutschland GmbH & Co. KG (DE) | 2017-07-11 | — | — | US | disclosed |
| EP-3150607-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2560973-B1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2016-11-16 | — | — | EP | disclosed |
| EP-2421870-B1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2522671-B1 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150175611-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-25 | — | — | US | disclosed |
| US-8846663-B2 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130310368-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC. | 2013-11-21 | — | — | US | disclosed |
| US-8546377-B2 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-7122699-B2 | Process for preparing organic boronic acid derivatives using diboronic acid | BORON MOLECULAR LIMITED (AU) | 2006-10-17 | — | — | US | disclosed |
| EP-1019414-B1 | PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID | COMMW SCIENT IND RES ORG (AU) | 2005-06-08 | — | — | EP | disclosed |
| US-20030220520-A1 | Process for preparing organic boronic acid derivatives using diboronic acid | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2003-11-27 | — | — | US | disclosed |
| US-6603004-B2 | Reacting diboron tetrahydroxide with boronic acid derivatives in presence of group 8-11 metal catalyst; one pot; no need for hydrolysis or hydrogenolysis | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2003-08-05 | — | — | US | disclosed |
| US-20020151743-A1 | Process for preparing organic boronic avid derivatives using diboronic acid | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-10-17 | — | — | US | disclosed |
| US-6448433-B1 | REACTING AN ORGANIC HALIDE WITH TETRAHYDROXYDIBORON; GROUP 8-11 METAL CATALYST | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 2002-09-10 | — | — | US | disclosed |
| EP-1019414-A4 | PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID | COMMW SCIENT IND RES ORG (AU) | 2002-05-29 | — | — | EP | disclosed |
| CN-1275984-A | Process for preparing organic boronic acid derivatives using diboronic acid | COMMW SCIENT IND RES ORG (AU) | 2000-12-06 | — | — | CN | disclosed |
| EP-1019414-A1 | PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999012940-A1 | PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220520-A1 | Process for preparing organic boronic acid derivatives using diboronic acid | BTD, BRAP, DBF4 | CA1 851/4885PAM 1550/4885MAOB 48/4885 |
| US-20130310368-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | CA1 2697/4885PAM 1392/4885MAOB 194/4885 |
| US-20020151743-A1 | Process for preparing organic boronic avid derivatives using diboronic acid | BTD, BRAP, BCL6B | CA1 1108/4885PAM 781/4885MAOB 193/4885 |
| US-20180127423-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | CA1 2697/4885PAM 1392/4885MAOB 194/4885 |
| US-20150175611-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | CA1 2697/4885PAM 1392/4885MAOB 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.