Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492577 | 0.91 | DCTPP1 (0.41) | DCTPP1ALDH1A1MAPK1PDE10ASPHK1 | |
| SCHEMBL6498493 | 0.78 | DCTPP1 (0.40) | DCTPP1PPARGALDH1A1MAPK1NPSR1 | |
| SCHEMBL6923118 | 0.76 | DHODH (0.33) | DCTPP1DHODH | |
| SCHEMBL6923121 | 0.76 | DCTPP1 (0.36) | DCTPP1DHODHAGTR1PPARG | |
| SCHEMBL6490602 | 0.76 | PPARG (0.41) | DCTPP1PPARGCYP2C9NPSR1 | |
| SCHEMBL6486764 | 0.75 | DCTPP1 (0.44) | DCTPP1DHODHAGTR1PPARGAGTR2 | |
| SCHEMBL6489174 | 0.74 | PIK3C2B (0.37) | DCTPP1DHODHAGTR1PPARG | |
| SCHEMBL6502677 | 0.74 | P2RX3 (0.40) | DCTPP1DHODHPDE10A | |
| SCHEMBL6493027 | 0.73 | MCL1 (0.43) | DHODHAGTR1AGTR2 | |
| SCHEMBL6501198 | 0.72 | NR4A2 (0.48) | DHODHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |