SCHEMBL6923610

SCHEMBL6923610

CCOC(=O)CC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PARP14 Q460N5 1/20 0.41
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
DGAT1 O75907 1/20 0.40
CHRM3 P20309 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13460034 0.82 AKR1C3 (0.48) CHRM3
SCHEMBL6928717 0.82 FFAR4 (0.44) CHRM3
SCHEMBL6925601 0.81 MEN1 (0.59) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL22657728 0.80 ATM (0.51) POLBL3MBTL1MEN1KMT2APARP14
SCHEMBL8544211 0.77 ACHE (0.56) L3MBTL1MEN1KMT2APARP14ALDH1A1
SCHEMBL8809184 0.77 DRD2 (0.61) DRD2DRD4
SCHEMBL1717843 0.77 POLB (0.38) POLBKMT2APARP14DGAT1ALDH1A1
SCHEMBL462769 0.77 CHRM3 (0.38) L3MBTL1CHRM3ALDH1A1
SCHEMBL21157388 0.76 OPRD1 (0.48) L3MBTL1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL9536536 0.76 DRD2 (0.60) DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed