Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460034 | 0.88 | AKR1C3 (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6923610 | 0.82 | POLB (0.45) | CHRM3 | |
| SCHEMBL6922044 | 0.81 | LTA4H (0.43) | CHRM3CHRM2CHRM1HRH1 | |
| SCHEMBL6926803 | 0.80 | MMP3 (0.46) | CHRM3CHRM2CHRM1 | |
| SCHEMBL10547718 | 0.79 | LTA4H (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL462769 | 0.78 | CHRM3 (0.38) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6929764 | 0.78 | CHRM3 (0.50) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5733825 | 0.78 | L3MBTL1 (0.49) | — | |
| SCHEMBL11223595 | 0.77 | CHRM3 (0.39) | FFAR4CHRM3CHRM2CHRM1ITGB3 | |
| SCHEMBL7959117 | 0.77 | MAOA (0.36) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| CN-1323307-A | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |