Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.47 |
| ▸ | CTSK | P43235 | 10/20 | 0.47 |
| ▸ | CTSS | P25774 | 8/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466927 | 0.88 | CTSL (0.48) | CTSLCTSKCTSSCTSBTAS1R3 | |
| SCHEMBL7463738 | 0.80 | TAS1R3 (0.45) | CTSLCTSKCTSSCTSBTAS1R3 | |
| SCHEMBL7464381 | 0.77 | CTSL (0.47) | CTSLCTSSCTSBTAS1R3TAS1R1 | |
| SCHEMBL6927425 | 0.76 | CTSL (0.55) | CTSLCTSKCTSSCTSB | |
| SCHEMBL6621993 | 0.76 | CTSK (0.54) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7462272 | 0.75 | CTSL (0.50) | CTSLCTSKCTSSCTSBTAS1R3 | |
| SCHEMBL7473976 | 0.75 | CTSL (0.49) | CTSLCTSKCTSSCTSB | |
| SCHEMBL6927525 | 0.75 | CTSL (0.49) | CTSLCTSKCTSSCTSBADORA3 | |
| SCHEMBL7467318 | 0.74 | CTSL (0.53) | CTSLCTSKCTSSCTSBF2 | |
| SCHEMBL7473777 | 0.74 | CTSL (0.53) | CTSLCTSKCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |