Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467592 | 0.91 | TAS1R3 (0.49) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL7466927 | 0.91 | CTSL (0.48) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL7462272 | 0.83 | CTSL (0.50) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL6927425 | 0.82 | CTSL (0.55) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7464381 | 0.82 | CTSL (0.47) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL7473345 | 0.81 | TAS1R3 (0.54) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL7467134 | 0.80 | CTSK (0.43) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL7461611 | 0.80 | CTSL (0.47) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL6923642 | 0.80 | CTSL (0.47) | TAS1R3TAS1R1CTSBCTSSCTSL | |
| SCHEMBL7473976 | 0.80 | CTSL (0.49) | CTSBCTSSCTSLCTSKKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983228-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-08-07 | — | — | EP | claimed |
| EP-0983228-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-08 | — | — | EP | claimed |
| WO-1998050342-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |