Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MELK | Q14680 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27803929 | 0.94 | HTR6 (0.54) | PNMTHTR6DRD2HTR2AHTR2C | |
| SCHEMBL3249580 | 0.86 | PNMT (0.62) | PNMTHTR6DRD2HTR2AHTR2C | |
| SCHEMBL7452220 | 0.80 | HTR6 (0.84) | PNMTHTR6DRD2HTR2AHTR2C | |
| SCHEMBL13757776 | 0.80 | PNMT (0.76) | PNMTHTR6DRD2HTR2AHTR2C | |
| SCHEMBL8115507 | 0.79 | HTR6 (0.55) | PNMTHTR6DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL10563577 | 0.79 | HTR6 (0.82) | PNMTHTR6DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9958844 | 0.79 | PNMT (0.74) | PNMTHTR6DRD2HTR2AHTR2C | |
| SCHEMBL7258770 | 0.78 | ALDH1A1 (0.58) | — | |
| Hydrochloric Acid SCHEMBL4789165 | 0.78 | HTR6 (0.54) | PNMTHTR6DRD2HTR2AHTR2C | |
| SCHEMBL6150374 | 0.77 | PNMT (0.85) | PNMTHTR6DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074256-A1 | TETRAHYDROISOQUINOLINYL SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | claimed |