Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18422825 | 0.83 | LMNA (0.64) | ALDH1A1SMN1; SMN2LMNATHRBL3MBTL1 | |
| SCHEMBL30023674 | 0.83 | LMNA (0.64) | ALDH1A1SMN1; SMN2LMNATHRBL3MBTL1 | |
| SCHEMBL27183420 | 0.80 | LMNA (0.60) | ALDH1A1SMN1; SMN2LMNATHRBL3MBTL1 | |
| SCHEMBL15220226 | 0.79 | LMNA (0.59) | ALDH1A1SMN1; SMN2LMNATHRBL3MBTL1 | |
| SCHEMBL27803929 | 0.78 | HTR6 (0.54) | — | |
| SCHEMBL6925873 | 0.78 | PNMT (0.56) | — | |
| SCHEMBL7262332 | 0.78 | TRPV1 (0.64) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL7262334 | 0.78 | TRPV1 (0.64) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL13369892 | 0.74 | NPC1 (0.53) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL22516003 | 0.74 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2LMNATHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |