Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132970 | 0.84 | SMN1; SMN2 (0.51) | HSD17B10SMN1; SMN2KMT2AMAPTTSHR | |
| SCHEMBL6829232 | 0.84 | NPC1 (0.50) | HSD17B10SMN1; SMN2KMT2AMAPTTSHR | |
| SCHEMBL6923514 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6829615 | 0.83 | ALDH1A1 (0.50) | HSD17B10SMN1; SMN2KMT2AMAPTTSHR | |
| SCHEMBL6441520 | 0.83 | DAO (0.49) | HSD17B10SMN1; SMN2KMT2AMAPTTSHR | |
| SCHEMBL6829041 | 0.83 | SMN1; SMN2 (0.41) | HSD17B10SMN1; SMN2KMT2AMAPTTSHR | |
| SCHEMBL6923684 | 0.80 | ALDH1A1 (0.44) | HSD17B10SMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL6919445 | 0.80 | MAOB (0.44) | KMT2ATSHRALDH1A1MEN1NPC1 | |
| SCHEMBL7133523 | 0.80 | NPC1 (0.60) | SMN1; SMN2KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6922355 | 0.78 | CYP1A2 (0.46) | HSD17B10SMN1; SMN2KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
| US-10875834-B2 | Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2020-12-29 | — | — | US | disclosed |
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875834-B2 | Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives | MTHFD1, MTHFD2, ADH5 | HSD17B10 527/4885SMN1; SMN2 384/4885KMT2A 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.