Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928332 | 0.88 | MLYCD (0.43) | MLYCDSLC6A4ICAM1SELENFE2L2 | |
| SCHEMBL6924085 | 0.77 | ERN1 (0.43) | GAAPTGESICAM1SELEMAPK1 | |
| SCHEMBL3544287 | 0.77 | MLYCD (0.46) | MLYCDSLC6A4GAANFE2L2SLC6A2 | |
| SCHEMBL6923230 | 0.77 | ERN1 (0.43) | GAAPTGESICAM1SELEMAPK1 | |
| SCHEMBL16508072 | 0.75 | SLC6A4 (0.50) | SLC6A4ICAM1SELESLC6A2SLC6A3 | |
| SCHEMBL6928500 | 0.75 | PDE7A (0.54) | SLC6A4GAAPTGESKIF11LMNA | |
| SCHEMBL6763816 | 0.75 | ERN1 (0.49) | GAAPTGESICAM1SELEMAPK1 | |
| SCHEMBL6923162 | 0.73 | LMNA (0.47) | GAAPTGESICAM1SELEMAPK1 | |
| SCHEMBL6925223 | 0.73 | ALDH1A1 (0.43) | GAAPTGESICAM1SELEMAPK1 | |
| SCHEMBL6927314 | 0.73 | CYP2A6 (0.43) | MLYCDICAM1SELENFE2L2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |