Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926438 | 0.88 | MLYCD (0.43) | MLYCDNPBWR1ICAM1SELENFE2L2 | |
| SCHEMBL16495054 | 0.85 | SLC6A2 (0.39) | NPBWR1SLC6A4SLC6A2SLC6A3HPGD | |
| SCHEMBL2799552 | 0.78 | POLB (0.37) | CYP1A1CYP1B1ALDH1A1MAPTLMNA | |
| SCHEMBL6927202 | 0.77 | TDP1 (0.46) | ICAM1SELEALDH1A1MAPTMEN1 | |
| SCHEMBL16508072 | 0.75 | SLC6A4 (0.50) | ICAM1SELESLC6A4SLC6A2SLC6A3 | |
| SCHEMBL31345540 | 0.75 | MAPT (0.52) | MLYCDSLC6A4SLC6A2SLC6A3HPGD | |
| SCHEMBL6926229 | 0.75 | ALDH1A1 (0.50) | ICAM1SELEHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9952937 | 0.74 | DDR1 (0.42) | L3MBTL1KIF11ALDH1A1MAPTLMNA | |
| SCHEMBL3544287 | 0.74 | MLYCD (0.46) | MLYCDNPBWR1NFE2L2SLC6A4SLC6A2 | |
| SCHEMBL3033291 | 0.73 | CYP1A1 (0.46) | NPBWR1NFE2L2CYP1A1CYP1B1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |