Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924599 | 0.91 | ADRA1A (0.57) | ADRA1AADRA1BADRA1DSLC6A4DRD2 | |
| SCHEMBL6926651 | 0.85 | DRD2 (0.55) | ADRA1AADRA1BADRA1DDRD4DRD2 | |
| SCHEMBL6928838 | 0.83 | DRD2 (0.48) | DRD2DRD3HTR1A | |
| SCHEMBL6925552 | 0.83 | DRD2 (0.50) | DRD4DRD2DRD3HTR1ALMNA | |
| SCHEMBL6923214 | 0.82 | DRD2 (0.47) | ADRA1AADRA1BADRA1DDRD4DRD2 | |
| SCHEMBL7344989 | 0.81 | HTR1A (0.64) | ADRA1AADRA1BADRA1DDRD4DRD2 | |
| SCHEMBL7351802 | 0.80 | HTR1A (0.58) | ADRA1AADRA1BADRA1DDRD4SLC6A4 | |
| SCHEMBL6928543 | 0.79 | DRD2 (0.43) | DRD4SLC6A4DRD2DRD3HTR1A | |
| SCHEMBL6926353 | 0.78 | ADRA1A (0.51) | ADRA1AADRA1BADRA1DSLC6A4DRD2 | |
| SCHEMBL6924603 | 0.76 | DRD3 (0.55) | DRD2DRD3HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120070-A1 | Serotonin 5-HT1A and dopamin D2 receptor ligands | H. LUNDBECK A/S (DE) | 2003-06-26 | — | — | US | disclosed |
| US-6514993-B1 | Useful in the treatment of certain psychic and neurologic disorders | H. LUNDBECK A/S (DK) | 2003-02-04 | — | — | US | disclosed |
| EP-0770066-B1 | SEROTONIN 5-HT 1A AND DOPAMIN D2 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2000-05-17 | — | — | EP | disclosed |
| EP-0770066-A1 | SEROTONIN 5-HT 1A AND DOPAMIN D2 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 1997-05-02 | — | — | EP | disclosed |
| WO-1995033729-A1 | SEROTONIN 5-HT1A AND DOPAMIN D2 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120070-A1 | Serotonin 5-HT1A and dopamin D2 receptor ligands | HTR5A, HTR2C, HTR1D | ADRA1A 110/4885ADRA1B 129/4885ADRA1D 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.