Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 12/20 | 0.61 |
| ▸ | GABRD | O14764 | 12/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.61 |
| ▸ | GABRE | P78334 | 12/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.61 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923209 | 0.77 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6928060 | 0.76 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7970280 | 0.72 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6926985 | 0.72 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7966892 | 0.67 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9768186 | 0.65 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6957234 | 0.64 | GABRA2 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10562426 | 0.63 | GABRA2 (0.58) | GABRB3GABRA2GABRB2 | |
| SCHEMBL6970770 | 0.63 | PKM (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7158950 | 0.63 | GABRA2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | claimed |
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | disclosed |