Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 17/20 | 0.57 |
| ▸ | GABRD | O14764 | 17/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 17/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 17/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 17/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 17/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 17/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 17/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 17/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 17/20 | 0.57 |
| ▸ | GABRE | P78334 | 17/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 17/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 17/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 17/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 17/20 | 0.57 |
| ▸ | PIEZO1 | Q92508 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966892 | 0.83 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7956709 | 0.76 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6928060 | 0.73 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7966297 | 0.72 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6926644 | 0.72 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8557605 | 0.66 | GABRA2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6970770 | 0.64 | PKM (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8556916 | 0.63 | IKBKB (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7970275 | 0.62 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4436528 | 0.62 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |